What I can't seem to find is what clues or warning signs to be on the look out for if your nozzle has taken a significant amount of wear. I've printed a few hundred grams of glow filament personally and have not noticed any change in print quality.
E3D says you may have "unpredictable erratic printing" with a worn nozzle. Can anyone explain or provide examples of what this actually means and when a replacement is necessary?
One of the things I look for is if you pull the print head a good ways off the bed and have it extrude. It should just squirt plastic straight down. If it bends sharply in one direction, or even curls back on itself, then that is a sign of damage.