One of my graduate students, doing their PhD in another university, is doing quite well. Recently, he told me that he is having a tussle with his supervisor on communication of his work to a specific journal. His supervisor insists he submit his research to a very high profile journal, but my student does not believe that his research work would be accepted by this journal. Side note: His supervisor does not have any publications in this high profile journal.
Now my question is that, how to deal with such situation?
Everyone should be so lucky to have an advisor who pushes them to excel and to aspire to the highest standards of achievement. Really, I don't see why your friend is complaining -- he should just go ahead and submit the paper to the high-profile journal.
Moreover, your friend's advisor, whether he published in the journal before or not, is considerably more qualified than your friend to judge the chances of the paper to be accepted to the journal. If the advisor thinks that's where the paper should be submitted, your friend would in all likelihood be foolish to disagree, especially since the worst that can happen is the paper will get rejected, probably sooner rather than later.
The only exception to this advice is in the bizarre situation in which the advisor is clearly delusional. In that case, your friend has much bigger problems and should probably look for a different advisor, not because of the small and self-correcting problem with the journal but because having an advisor who is so delusional and has such poor judgment does not bode well for your friend's eventual success in his research.