It occurs to me that I'm never really thinking about layer height when I calibrate my z-probe offset. This is obviously an oversight, because I'll want my nozzle to start higher for 0.3mm layers than for 0.1mm layers.
After this realization comes the question: Do I need to recalibrate every time I switch to a different layer height? Or can slicers store a reference layer height + probe offset and just deduce the proper starting height for every print? Or is it smartest to keep the 1st layer height constant throughout my prints to spare myself this frustration?
If it matters, my printer is the Printrbot Simple Metal, and my goto slicer is Cura.
The first layer is usually squished more to help with the adhesion. On top of that with ABS there's a bit of deformation even if the print doesn't lift. So spare yourself the frustration, FDM 3d printers aren't that precise themselves for you to care about this.